Validation of a new strategy for the identification of SARS-CoV-2 variants by sequencing the spike gene by SangerArticle Published on 2023-05-012023-07-11 Journal: Enfermedades infecciosas y microbiologia clinica ( [Category] COVID19(2023년), [키워드] Mutaciones mutations next generation sequencing Proteína Espiga Sanger sequencing SARS-CoV-2 Secuenciación de nueva generación Secuenciación Sanger Spike protein Variante de interés Variante de preocupación variants of concern variants of interest. [DOI] 10.1016/j.eimce.2022.10.003 PMC 바로가기
Loss of furin site enhances SARS-CoV-2 spike protein pseudovirus infectionArticle Published on 2023-03-102023-07-11 Journal: Gene [Category] COVID19(2023년), [키워드] COVID-19 furin SARS-CoV-2 Spike protein Viral pseudotyping. [DOI] 10.1016/j.gene.2022.147144 PMC 바로가기
The spike effect of acute respiratory syndrome coronavirus 2 and coronavirus disease 2019 vaccines on blood pressureReview Published on 2023-03-012023-07-11 Journal: European journal of internal medicine [Category] COVID19(2023년), [키워드] ACE2 blood pressure COVID-19 COVID-19 vaccination hypertension renin-angiotensin system SARS-CoV-2 Spike protein Vaccines. [DOI] 10.1016/j.ejim.2022.12.004 PMC 바로가기 [Article Type] Review
Interactions of angiotensin-converting enzyme-2 (ACE2) and SARS-CoV-2 spike receptor-binding domain (RBD): a structural perspectiveReview Published on 2023-03-012023-07-11 Journal: Molecular biology reports [Category] COVID19(2023년), [키워드] ACE2 renin-angiotensin system SARS-CoV-2 Spike protein spike variants. [DOI] 10.1007/s11033-022-08193-4 PMC 바로가기 [Article Type] Review
The Spike protein of SARS-CoV-2 signals via Tlr2 in zebrafishArticle Published on 2023-03-012023-07-11 Journal: Developmental and comparative immunology [Category] COVID19(2023년), [키워드] Hematopoiesis Inflammation interleukin-1 Spike protein TLRs zebrafish. [DOI] 10.1016/j.dci.2022.104626 PMC 바로가기
Structural patterns of SARS-CoV-2 variants of concern (alpha, beta, gamma, delta) spike protein are influenced by variant-specific amino acid mutations: A computational study with implications on viral evolutionArticle Published on 2023-02-072023-07-11 Journal: Journal of theoretical biology [Category] COVID19(2023년), [키워드] SARS-CoV-2 (SARS2) Spike protein Structural pattern Variant-specific amino acid variants of concern. [DOI] 10.1016/j.jtbi.2022.111376 PMC 바로가기
Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen applicability applied approach Cellulose Concentration COVID-19 diagnosis CR3022 detect diagnostic Differential pulse voltammetry expressed functional group limit of detection linear relationship monoclonal antibody nasopharyngeal swab sample Nicotiana benthamiana Paper-based electrochemical immunosensor Plant-based antibody platform point-of-care pulse quantification RBD Receptor binding domain Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. Spike protein the RBD this system was performed [DOI] 10.1016/j.talanta.2022.123783 PMC 바로가기
A comprehensive review of SARS-CoV-2 vaccines: Pfizer, Moderna & Johnson & JohnsonSARS-CoV-2 백신에 대한 포괄적인 검토: Pfizer, Moderna & Johnson & JohnsonReview Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] Adenovirus administration age approval clinical clinical trial clinical trials coronavirus coronavirus. COVID-19 COVID-19 vaccine COVID-19 vaccines effective Efficacy General population group Johnson Johnson & Johnson Johnson & large cohort mechanism moderate Moderna mRNA vaccines Novel coronavirus ongoing trial ongoing trials outbreak pandemic participant Pfizer Safety SARS-CoV-2 SARS-CoV-2 coronavirus SARS-COV-2 infection shown Side effects Spike protein symptomatic SARS-CoV-2 infection tested the SARS-CoV-2 the spike protein the United State Trial United States Vaccinations Vaccine vaccine administration variant [DOI] 10.1080/21645515.2021.2002083 PMC 바로가기 [Article Type] Review
Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model마우스 모델에서 SARS-CoV-2 공격에 대한 보호 반응 유도에 대한 최적화된 서열과 SARS-CoV-2의 스파이크 단백질 야생형 DNA 서열의 비교Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 비임상, 진단, [키워드] acid Against Antiviral binding breath CD4 CD8+ cellular immune responses cellular immunity challenge clinical trial contributing to COVID-19 CTL demonstrated DNA DNA vaccine expression full-length spike protein hACE2 humoral humoral and cellular immunity IFN-γ immune immune responses immunogen in vitro induction mice Model mouse Neutralizing antibodies optimization optimizations pGX-9501 platform Protective Protective effects protective response RBD binding response robust SARS-CoV-2 sequence spike Spike protein subsequent T cell T cells the vaccine Transgenic mouse Type virus wild-type wild-type sequence. [DOI] 10.1080/21645515.2021.2016201 PMC 바로가기 [Article Type] Article
Two-Period Study Results from a Large Italian Hospital Laboratory Attesting SARS-CoV-2 Variant PCR Assay EvolutionArticle Published on 2022-12-212023-07-10 Journal: Microbiology Spectrum [Category] COVID19(2023년), [키워드] Amino acid mutation Next-generation sequencing PCR assay SARS-CoV-2 Spike protein variant detection. [DOI] 10.1128/spectrum.02922-22 PMC 바로가기